TRT has certain risks and benefits, so your healthcare provider will carefully evaluate if it’s safe and right for you. However, when given to men with hypogonadism in the short- and medium-term, testosterone replacement therapy does not increase the risk of cardiovascular events (including strokes and heart attacks and other heart diseases). Adverse effects of testosterone supplementation may include increased cardiovascular events (including strokes and heart attacks) and deaths based on three peer-reviewed studies involving men taking testosterone replacement. The high doses of testosterone required to increase sexual desire in women may have a significant risk of masculinization with long-term therapy. For men who clearly have testosterone deficiency, there is no apparent increased risk of heart attack or stroke or greater chance of developing a new prostate cancer from testosterone replacement therapy. When prescribed and monitored by healthcare professionals, testosterone gel provides a safe and effective path for gender affirmation and physical transition. Yes, avoid skin-to-skin contact until the gel has fully dried, and wash your hands thoroughly after applying. It contains varying concentrations depending on the brand, such as Testogel, Tostran, Androgel, Testavan, or Testim. The FDA approved Androgel in February 2000. Androgel belongs to a class of drugs called androgens. Stop using topical testosterone and get emergency help if you have any of the following signs of blood clots. In severe cases, it may increase your risk for blood clots. This can increase hemoglobin levels in your blood. Topical testosterone may increase your risk of prostate cancer. Testosterone levels in men often decrease with age. There aren't studies to back up using it for other symptoms. That's made it interesting as a possible remedy for menopause symptoms like depression, bone loss, and sexual problems. Beyond puberty, a woman's body mainly converts it to estrogen. After applying topical testosterone, do not go near an open flame or smoke until the product dries. Women and children should avoid coming in contact with the area where you applied the medicine because of the risk of side effects. After applying topical testosterone, wash your hands well with soap and water right away. Do not apply topical testosterone to other areas not recommended in the product instructions, such as your stomach, penis, or scrotum.
